Many individuals have dedicated their research to study multiple sclerosis (MS). MS is an autoimmune disease that targets the central nervous system (CNS). Because of this, one can be potentially disabled by damaging the nerves. There are two tissues in the brain that can be affected by MS— the gray and white matter (myelinated) in Harrisburg, PA.
As an integral part of the nervous system, white matter (myelinated) in Harrisburg, PA contains the axons that connect the nerves and conduct the signals among the other nerve cell bodies. Unlike the gray ones that form the cerebral cortex as an outer layer, white matter (myelinated) in Harrisburg, PA can be found in the subcortical section or the brain’s deeper and inner tissues.
How Multiple Sclerosis Affects White Matter (Myelinated) in Harrisburg, PA
Most studies conclude that multiple sclerosis is a disease primarily concerning white matter (myelinated) in Harrisburg, PA. This is because MS targets the immune system by attacking the tissues protecting white matter (myelinated) in Harrisburg, PA. Here are some examples of the issues in white matter (myelinated) in Harrisburg, PA that are caused by MS:
MS Elicits an Abnormal Immune Response on White Matter (Myelinated) in Harrisburg, PA
There are many changes in white matter (myelinated) in Harrisburg, PA that are caused by MS, such as the different immune responses on the conduction of cells. When the disease attacks the parts of the CNS, including white matter (myelinated) in Harrisburg, PA, it results in inflammation. This condition then turns to scarring, or also known as sclerosis in the medical field.
MS Causes Damage on the Protective Sheath of White Matter (Myelinated) in Harrisburg, PA
One of the characteristics that differentiate white matter (myelinated) in Harrisburg, PA from gray matter is its protective sheath, the myelin. This is what gives white matter (myelinated) in Harrisburg, PA its color. In the case of MS, the disease damages the white matter (myelinated) in Harrisburg, PA, as if it’s stripping off the nerve fibers of their shielding coat.
MS Damages the Nerve Fibers on White Matter (Myelinated) in Harrisburg, PA
Once the protective sheath is gone, MS attacks the axons of white matter (myelinated) in Harrisburg, PA. When this happens, it can cause individuals to experience negative changes in their mood, muscle strength, balance, and vision. These symptoms of the injury on white matter (myelinated) in Harrisburg, PA can last for weeks or months, depending on the damage.
MS Interrupts Nerve Signal Movement of White Matter (Myelinated) in Harrisburg, PA
Having MS can greatly affect a person’s functions. When the disease attacks white matter (myelinated) in Harrisburg, PA, it disrupts the communication among the nerve cells, which have the axons as their extensions. These cells that are connected to white matter (myelinated) in Harrisburg, PA transmit the signals throughout the body for it to operate.
Symptoms of Damaged White Matter (Myelinated) in Harrisburg, PA
Having an injury in the CNS will cause negative effects on the other systems of the body. An individual may be experiencing symptoms of damaged white matter (myelinated) in Harrisburg, PA through several conditions.
If a person is having trouble focusing, dealing with memory loss, and feeling fatigued, it is possible that the brain’s white matter (myelinated) in Harrisburg, PA is damaged. Other symptoms include numbness and tingling in some body parts and blurry or double vision.
Learn More About White Matter (Myelinated) in Harrisburg, PA at Multiple Sclerosis Research Institute
We are committed to discovering the cause, development, and cure of MS at Multiple Sclerosis Research Institute. Our team conducts laboratory research on the subject, including white matter (myelinated) in Harrisburg, PA. We can educate patients and other health care professionals on the effects of MS on white matter (myelinated) in Harrisburg, PA.
To be able to continue doing research, we seek funding from individuals and corporations to improve our facilities. Learn more about our non-profit organization on our website today.
Multiple Sclerosis Research Institute
Our non-profit foundation was started by Dr. Jeffrey Greenstein to Find, Stop and Cure MS. We focus on:
Conducting basic laboratory research into the cause and development of MS.
Developing translational research – moving from the laboratory to clinical applications – to foster new and innovative MS treatments.
Providing MS education for the public, including patients, caregivers, health care professionals, and MS specialists.
With our newly created laboratory and the hiring of proper research personnel, we have been experiencing an exciting season of development and growth. Right now is the perfect time for us to push for new studies and discoveries with support from the public.
Our Research
Multiple Sclerosis Research Institute is committed to conducting the highest quality laboratory-based research. The following are just some of our publications:
- Greenstein JI: Diffuse dermatophytosis occurring on dimethyl fumarate therapy Multiple Sclerosis Journal 2018:24(7) 999-1001
- Editorial comment on the paper: Correale J: New fungal infections associated with disease-modifying treatments in MS Multiple Sclerosis Journal 2018: 24(7) 1004-1006.
- Cunningham TJ, Greenstein JI, Yao L, Fischer I, Connors T. Heptamer Peptide Disassembles Native Amyloid in Human Plasma Through Heat Shock Protein 70.
- Cunningham, TJ, Oetinger, M, Blankenhorn EP, Greenstein, JI. Secreted Phospholipase A2 activity in experimental allergic encephalomyelitis and multiple sclerosis. Journal of Neuroinflammation 2006; 3:26
- Greenstein JI. Current concepts of the cellular and molecular pathophysiology of Multiple Sclerosis. Developmental Neurobiology 2008; 67:1248-1265.
- Cunningham, TJ, Greenstein, JI et al. Uncompetitive Phospholipase A2 inhibition by CHEC sequences including oral treatment of experimental autoimmune myeloencephalitis. The Open Enzyme Inhibition Journal 2009; 2:1-7.
- Greenstein JI, Cunningham TJ. Neuroprotective, Anti-inflammatory and Immune Tolerizing properties of peptides derived from Diffusion Survival Evasion Protein (DSEP)/Dermcidin. Academy of Neurology Annual Meeting April, 2014.
- Cunningham TJ, Greenstein JI, Loewenstein J, Degermentzidis. Anti-inflammatory peptide regulates supply of heat shock protein 70 monomers: Implications for aging and aging-related disease. Rejuvenation Research. 2015. 18(2):136-144.
- Buckle G, Bandari BD, Greenstein JI, et al. Effect of delayed-release Dimethyl Fumarate on lymphocyte subsets in patients with Relapsing Multiple Sclerosis: Interim analysis of REALIZE. Consortium of Multiple Sclerosis Centers. 2016 Annual Meeting.
Get Involved
If you’re also a firm believer of what we do here at Multiple Sclerosis Research Institute, there are several ways for you to get involved and help. Here are some of them:
- Volunteer
We’re seeking volunteers who will work to promote our well-defined mission to supporting entities. Anyone interested is welcome to submit a volunteer form through our website.
- Donate
As a fully incorporated 501(c)(3) non-profit foundation, the MSRI gets funding from individuals, corporations, foundations, and other organizations to continue what we do. Funding is crucial to ensure appropriate facilities and staffing for significant MS research. Without donations, we cannot continue our research and other programs.
Tax-deductible contributions are much appreciated. Checks made payable to “Multiple Sclerosis Research Institute” can be mailed to our address. You may also opt to contribute stock; contact us for the transfer information. For donations that will be made through credit card, PayPal, or GoFundMe, kindly visit our donation page for our links. We value any amount.
- Amazon Smile
Shop and help. For Amazon shoppers out there, we’re part of the charitable organizations under the AmazonSmile Foundation program. Pick us, Multiple Sclerosis Research Institute (“MSRI”), as your charity of choice the next time you check out your cart from smile.amazon.com.
- Buy From Our Shop
We sell hockey jerseys, pucks, and game tickets on our online shop. Proceeds will go to our funding. View them today and add to cart now.
Contact Us
Get in touch with Multiple Sclerosis Research Institute today for more information about us, what we do, and what we can do for you. You may also contact us if you would like to donate or volunteer. Anyone looking to learn more about multiple sclerosis is also welcome to reach out to us. We look forward to hearing from you soon.
Multiple Sclerosis Research Institute
Penn Treaty Park Place
1341 N. Delaware Ave Suite 213
Philadelphia PA 19125
Office — (267) 687-7027
Fax — (267) 687-7466
Email: info@msresearchinstitute.org